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The tendency to recreate ancestral CG dinucleotides in the human genome
BACKGROUND: The CG dinucleotides are known to be deficient in the human genome, due to a high mutation rate from 5-methylated CG to TG and its complementary pair CA. Meanwhile, many cellular functions rely on these CG dinucleotides, such as gene expression controlled by cytosine methylation status....
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025853/ https://www.ncbi.nlm.nih.gov/pubmed/21208429 http://dx.doi.org/10.1186/1471-2148-11-3 |