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Antigenic analysis of classical swine fever virus E2 glycoprotein using pig antibodies identifies residues contributing to antigenic variation of the vaccine C-strain and group 2 strains circulating in China

BACKGROUND: Glycoprotein E2, the immunodominant protein of classical swine fever virus (CSFV), can induce neutralizing antibodies and confer protective immunity in pigs. Our previous phylogenetic analysis showed that subgroup 2.1 viruses branched away from subgroup 1.1, the vaccine C-strain lineage,...

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Detalles Bibliográficos
Autores principales: Chen, Ning, Tong, Chao, Li, Dejiang, Wan, Jing, Yuan, Xuemei, Li, Xiaoliang, Peng, Jinrong, Fang, Weihuan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025870/
https://www.ncbi.nlm.nih.gov/pubmed/21194462
http://dx.doi.org/10.1186/1743-422X-7-378