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Polymorphisms in the SULF1 gene are associated with early age of onset and survival of ovarian cancer
BACKGROUND: SULF1 (sulfatase 1) selectively removes the 6-O-sulphate group from heparan sulfate, changing the binding sites for extracellular growth factors. SULF1 expression has been reported to be decreased in various cancers, including ovarian cancer. We hypothesized that single nucleotide polymo...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025876/ https://www.ncbi.nlm.nih.gov/pubmed/21214932 http://dx.doi.org/10.1186/1756-9966-30-5 |