Analgesic effect of highly reversible ω-conotoxin FVIA on N type Ca(2+ )channels

BACKGROUND: N-type Ca(2+ )channels (Ca(v)2.2) play an important role in the transmission of pain signals to the central nervous system. ω-Conotoxin (CTx)-MVIIA, also called ziconotide (Prialt(®)), effectively alleviates pain, without causing addiction, by blocking the pores of these channels. Unfort...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Seungkyu, Kim, Yoonji, Back, Seung Keun, Choi, Hee-Woo, Lee, Ju Yeon, Jung, Hyun Ho, Ryu, Jae Ha, Suh, Hong-Won, Na, Heung Sik, Kim, Hyun Jeong, Rhim, Hyewhon, Kim, Jae Il
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025903/
https://www.ncbi.nlm.nih.gov/pubmed/21172037
http://dx.doi.org/10.1186/1744-8069-6-97

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025903/
https://www.ncbi.nlm.nih.gov/pubmed/21172037
http://dx.doi.org/10.1186/1744-8069-6-97

Ejemplares similares