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Structure and Function of ABCG2-Rich Extracellular Vesicles Mediating Multidrug Resistance
Multidrug resistance (MDR) is a major impediment to curative cancer chemotherapy. The ATP-Binding Cassette transporters ABCG2, ABCB1 and ABCC2 form a unique defense network against multiple structurally and functionally distinct chemotherapeutics, thereby resulting in MDR. Thus, deciphering novel me...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025911/ https://www.ncbi.nlm.nih.gov/pubmed/21283667 http://dx.doi.org/10.1371/journal.pone.0016007 |