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Hypermethylation of Tumor Suppressor Genes Involved in Critical Regulatory Pathways for Developing a Blood-Based Test in Breast Cancer

BACKGROUND: Aberrant DNA methylation patterns might be used as a biomarker for diagnosis and management of cancer patients. METHODS AND FINDINGS: To achieve a gene panel for developing a breast cancer blood-based test we quantitatively assessed the DNA methylation proportion of 248 CpG sites per sam...

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Detalles Bibliográficos
Autores principales: Radpour, Ramin, Barekati, Zeinab, Kohler, Corina, Lv, Qing, Bürki, Nicole, Diesch, Claude, Bitzer, Johannes, Zheng, Hong, Schmid, Seraina, Zhong, Xiao Yan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025923/
https://www.ncbi.nlm.nih.gov/pubmed/21283676
http://dx.doi.org/10.1371/journal.pone.0016080