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Treatment with a corticotrophin releasing factor 2 receptor agonist modulates skeletal muscle mass and force production in aged and chronically ill animals

BACKGROUND: Muscle weakness is associated with a variety of chronic disorders such as emphysema (EMP) and congestive heart failure (CHF) as well as aging. Therapies to treat muscle weakness associated with chronic disease or aging are lacking. Corticotrophin releasing factor 2 receptor (CRF2R) agoni...

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Detalles Bibliográficos
Autores principales: Hinkle, Richard T, Lefever, Frank R, Dolan, Elizabeth T, Reichart, Deborah L, Zwolshen, Janice M, Oneill, Timothy P, Maloney, Kris G, Mattson, John P, Ferreira, Leonardo F, Musch, Timothy I, Poole, David C, Isfort, Robert J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025927/
https://www.ncbi.nlm.nih.gov/pubmed/21235761
http://dx.doi.org/10.1186/1471-2474-12-15