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Treatment with a corticotrophin releasing factor 2 receptor agonist modulates skeletal muscle mass and force production in aged and chronically ill animals
BACKGROUND: Muscle weakness is associated with a variety of chronic disorders such as emphysema (EMP) and congestive heart failure (CHF) as well as aging. Therapies to treat muscle weakness associated with chronic disease or aging are lacking. Corticotrophin releasing factor 2 receptor (CRF2R) agoni...
Autores principales: | Hinkle, Richard T, Lefever, Frank R, Dolan, Elizabeth T, Reichart, Deborah L, Zwolshen, Janice M, Oneill, Timothy P, Maloney, Kris G, Mattson, John P, Ferreira, Leonardo F, Musch, Timothy I, Poole, David C, Isfort, Robert J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025927/ https://www.ncbi.nlm.nih.gov/pubmed/21235761 http://dx.doi.org/10.1186/1471-2474-12-15 |
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