Stable isotope shifted matrices enable the use of low mass ion precursor scanning for targeted metabolite identification

We describe a method to identify metabolites of proteins that eliminates endogenous background by using stable isotope labeled matrices. This technique allows selective screening of the intact therapeutic molecule and all metabolites using a modified precursor ion scan that monitors low molecular we...

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Detalles Bibliográficos
Autores principales: Reilly, Charles B, Ramarathinam, Sri H, Williamson, Nicholas A, Purcell, Anthony W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025931/
https://www.ncbi.nlm.nih.gov/pubmed/21241510
http://dx.doi.org/10.1186/1477-5956-9-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025931/
https://www.ncbi.nlm.nih.gov/pubmed/21241510
http://dx.doi.org/10.1186/1477-5956-9-2

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