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Stable isotope shifted matrices enable the use of low mass ion precursor scanning for targeted metabolite identification
We describe a method to identify metabolites of proteins that eliminates endogenous background by using stable isotope labeled matrices. This technique allows selective screening of the intact therapeutic molecule and all metabolites using a modified precursor ion scan that monitors low molecular we...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025931/ https://www.ncbi.nlm.nih.gov/pubmed/21241510 http://dx.doi.org/10.1186/1477-5956-9-2 |