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The mitochondrial DNA 4,977-bp deletion and its implication in copy number alteration in colorectal cancer
BACKGROUND: Qualitative and quantitative changes in human mitochondrial DNA (mtDNA) have been implicated in various cancer types. A 4,977 bp deletion in the major arch of the mitochondrial genome is one of the most common mutations associated with a variety of human diseases and aging. METHODS: We c...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025938/ https://www.ncbi.nlm.nih.gov/pubmed/21232124 http://dx.doi.org/10.1186/1471-2350-12-8 |