Cargando…

The mitochondrial DNA 4,977-bp deletion and its implication in copy number alteration in colorectal cancer

BACKGROUND: Qualitative and quantitative changes in human mitochondrial DNA (mtDNA) have been implicated in various cancer types. A 4,977 bp deletion in the major arch of the mitochondrial genome is one of the most common mutations associated with a variety of human diseases and aging. METHODS: We c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Tao, He, Jing, Shen, Lijun, Fang, Hezhi, Nie, Hezhongrong, Jin, Tao, Wei, Xiaosong, Xin, Yijuan, Jiang, Yulin, Li, Hongzhi, Chen, Guorong, Lu, Jianxin, Bai, Yidong
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025938/ https://www.ncbi.nlm.nih.gov/pubmed/21232124 http://dx.doi.org/10.1186/1471-2350-12-8

Ejemplares similares

Analysis of the Mitochondrial 4977 Bp Deletion in Patients with Hepatocellular Carcinoma
por: Guo, ZS, et al.
Publicado: (2017)

Detection of mitochondrial DNA with 4977 bp deletion in leukocytes of patients with ischemic stroke
por: Huang, Yu-hua, et al.
Publicado: (2018)

Correlation of the 4977 bp mitochondrial DNA deletion with human sperm dysfunction
por: Ieremiadou, Fotini, et al.
Publicado: (2009)

Mitochondrial DNA 4977 bp Deletion in Chronic Cervicitis and Cervix Cancers
por: Kara, M, et al.
Publicado: (2012)

A comprehensive overview of mitochondrial DNA 4977-bp deletion in cancer studies
por: Yusoff, Abdul Aziz Mohamed, et al.
Publicado: (2019)

Correlation between mitochondrial DNA 4977 bp deletion and presbycusis: A system review and meta-analysis
por: Han, Baoai, et al.
Publicado: (2019)

Deletion of a 4977-bp Fragment in the Mitochondrial Genome Is Associated with Mitochondrial Disease Severity
por: Zhang, Yanchun, et al.
Publicado: (2015)

Mitochondrial DNA 4977 bp Deletion in Peripheral Blood Is Associated With Polycystic Ovary Syndrome
por: Ye, Mujin, et al.
Publicado: (2021)

Common 4977 bp deletion and novel alterations in mitochondrial DNA in Vietnamese patients with breast cancer
por: Dimberg, Jan, et al.
Publicado: (2015)

Association of large scale 4977-bp “common” deletions in sperm mitochondrial DNA with asthenozoospermia and oligoasthenoteratozoospermia
por: Ambulkar, Prafulla S., et al.
Publicado: (2016)

Growth Retardation in the Course of Fanconi Syndrome Caused by the 4977-bp Mitochondrial DNA Deletion: A Case Report
por: Li, Ting, et al.
Publicado: (2021)

Mitochondrial Common Deletion, a Potential Biomarker for Cancer Occurrence, Is Selected against in Cancer Background: A Meta-Analysis of 38 Studies
por: Nie, Hezhongrong, et al.
Publicado: (2013)

Detection of 4977-bp deletion of mitochondrial DNA in in vitro fertilization failure women: A case-control study
por: Mirabutalebi, Seyed Hamidreza, et al.
Publicado: (2018)

Increases in Mitochondrial DNA Content and 4977-bp Deletion upon ATM/Chk2 Checkpoint Activation in HeLa Cells
por: Niu, Rong, et al.
Publicado: (2012)

Mitochondrial DNA 4977bp Deletion Mutation in Peripheral Blood Reflects Atrial Remodeling in Patients with Non-Valvular Atrial Fibrillation
por: Lee, Jihei Sara, et al.
Publicado: (2015)

Nested PCR for mtDNA-4977-bp deletion and comet assay for DNA damage - a combined method for radiosensitivity evaluation of tumor cells
por: LI, JIANGUO, et al.
Publicado: (2014)

Cancer type-specific modulation of mitochondrial haplogroups in breast, colorectal and thyroid cancer
por: Fang, Hezhi, et al.
Publicado: (2010)

Independent and Combined Effects of Telomere Shortening and mtDNA(4977) Deletion on Long-term Outcomes of Patients with Coronary Artery Disease
por: Vecoli, Cecilia, et al.
Publicado: (2019)

Comparing copy-number profiles under multi-copy amplifications and deletions
por: Cordonnier, Garance, et al.
Publicado: (2020)

P977: THE VENOUS THROMBOEMBOLISM RISK ASSESMENT MODELS IN MULTIPLE MYELOMA
por: Alp Kirkizlar, Tugcan, et al.
Publicado: (2023)

Rare Copy Number Deletions Predict Individual Variation in Intelligence
por: Yeo, Ronald A., et al.
Publicado: (2011)

Identification of copy number variations and common deletion polymorphisms in cattle
por: Bae, Joon Seol, et al.
Publicado: (2010)

Insertion-deletions burden in copy number polymorphisms of the Tibetan population
por: Veerappa, Avinash M., et al.
Publicado: (2014)

977 Impact of Decolonization on Methicillin-resistant Staphylococcus aureus Transmission in Hospitalized Neonates
por: Popoola, Victor, et al.
Publicado: (2014)

977. Bacterial STI Diagnoses as Missed Opportunities for HIV Pre-Exposure Prophylaxis
por: Reddy, Archana K, et al.
Publicado: (2020)

Copy number analysis of NIPBL in a cohort of 510 patients reveals rare copy number variants and a mosaic deletion
por: Cheng, Yu-Wei, et al.
Publicado: (2014)

No signs of neurodegenerative effects in 15q11.2 BP1-BP2 copy number variant carriers in the UK Biobank
por: Boen, Rune, et al.
Publicado: (2023)

Alteration of the copy number and deletion of mitochondrial DNA in human hepatocellular carcinoma
por: Yin, P H, et al.
Publicado: (2004)

Identification of genomic functional hotspots with copy number alteration in liver cancer
por: Hsiao, Tzu-Hung, et al.
Publicado: (2013)

Copy number analysis reveals a novel multiexon deletion of the COLQ gene in congenital myasthenia
por: Wang, Wei, et al.
Publicado: (2016)

Prediction of a deletion copy number variant by a dense SNP panel
por: Kadri, Naveen K, et al.
Publicado: (2012)

Role of p16 deletion and Bmi1 copy number variation in glioma
por: Chetan, GK, et al.
Publicado: (2014)

Copy Number Deletion Has Little Impact on Gene Expression Levels in Racehorses
por: Park, Kyung-Do, et al.
Publicado: (2014)

Detection of de novo copy number deletions from targeted sequencing of trios
por: Fu, Jack M, et al.
Publicado: (2019)

Candidate targets of copy number deletion events across 17 cancer types
por: Huang, Qingyao, et al.
Publicado: (2023)

977. An Innovative 3-Year Medical Student Spiral Curriculum in Antimicrobial Stewardship and Infectious Diseases
por: Chin-Hong, Peter, et al.
Publicado: (2018)

The repertoire of copy number alteration signatures in human cancer
por: Tao, Ziyu, et al.
Publicado: (2023)

Muscle Mitochondrial DNA Copy Number, Deletion Mutation Frequency, and Physical Performance in Older Adults
por: Wanagat, Jonathan, et al.
Publicado: (2020)

Induction of long-term potentiation at Schaffer collateral-CA1 synapses in mice hippocampus after IMPX977 administration
por: Song, Ni, et al.
Publicado: (2020)

977. The Prevalence and Burden of Non-AIDS Co-Morbidities in Women with or At-risk for HIV Infection in the United States
por: Collins, Lauren F, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_15puaiusgq4s7qb093botvhufo