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Sustained Delivery of Activated Rho GTPases and BDNF Promotes Axon Growth in CSPG-Rich Regions Following Spinal Cord Injury

BACKGROUND: Spinal cord injury (SCI) often results in permanent functional loss. This physical trauma leads to secondary events, such as the deposition of inhibitory chondroitin sulfate proteoglycan (CSPG) within astroglial scar tissue at the lesion. METHODOLOGY/PRINCIPAL FINDINGS: We examined wheth...

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Detalles Bibliográficos
Autores principales: Jain, Anjana, McKeon, Robert J., Brady-Kalnay, Susann M., Bellamkonda, Ravi V.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026041/
https://www.ncbi.nlm.nih.gov/pubmed/21283639
http://dx.doi.org/10.1371/journal.pone.0016135