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In Vitro Assessment of Developmental Neurotoxicity: Use of Microelectrode Arrays to Measure Functional Changes in Neuronal Network Ontogeny

Because the Developmental Neurotoxicity Testing Guidelines require large numbers of animals and is expensive, development of in vitro approaches to screen chemicals for potential developmental neurotoxicity is a high priority. Many proposed approaches for screening are biochemical or morphological,...

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Detalles Bibliográficos
Autores principales: Robinette, Brian L., Harrill, Joshua A., Mundy, William R., Shafer, Timothy J.
Formato: Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026483/
https://www.ncbi.nlm.nih.gov/pubmed/21270946
http://dx.doi.org/10.3389/fneng.2011.00001