Pretreatment with a novel aquaporin 4 inhibitor, TGN-020, significantly reduces ischemic cerebral edema

We investigated the in vivo effects of a novel aquaporin 4 (AQP4) inhibitor 2-(nicotinamide)-1,3,4-thiadiazole, TGN-020, in a mouse model of focal cerebral ischemia using 7.0-T magnetic resonance imaging (MRI). Pretreatment with TGN-020 significantly reduced brain edema associated with brain ischemi...

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Detalles Bibliográficos
Autores principales: Igarashi, Hironaka, Huber, Vincent J., Tsujita, Mika, Nakada, Tsutomu
Formato: Texto
Lenguaje:English
Publicado: Springer Milan 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026762/
https://www.ncbi.nlm.nih.gov/pubmed/20924629
http://dx.doi.org/10.1007/s10072-010-0431-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026762/
https://www.ncbi.nlm.nih.gov/pubmed/20924629
http://dx.doi.org/10.1007/s10072-010-0431-1

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