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Mechanism of Inhibition of Enveloped Virus Membrane Fusion by the Antiviral Drug Arbidol

The broad-spectrum antiviral arbidol (Arb) inhibits cell entry of enveloped viruses by blocking viral fusion with host cell membrane. To better understand Arb mechanism of action, we investigated its interactions with phospholipids and membrane peptides. We demonstrate that Arb associates with phosp...

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Detalles Bibliográficos
Autores principales: Teissier, Elodie, Zandomeneghi, Giorgia, Loquet, Antoine, Lavillette, Dimitri, Lavergne, Jean-Pierre, Montserret, Roland, Cosset, François-Loïc, Böckmann, Anja, Meier, Beat H., Penin, François, Pécheur, Eve-Isabelle
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026800/
https://www.ncbi.nlm.nih.gov/pubmed/21283579
http://dx.doi.org/10.1371/journal.pone.0015874