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Insulin and Glucagon Regulate Pancreatic α-Cell Proliferation

Type 2 diabetes mellitus (T2DM) results from insulin resistance and β-cell dysfunction, in the setting of hyperglucagonemia. Glucagon is a 29 amino acid peptide hormone, which is secreted from pancreatic α cells: excessively high circulating levels of glucagon lead to excessive hepatic glucose outpu...

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Detalles Bibliográficos
Autores principales: Liu, Zhuo, Kim, Wook, Chen, Zhike, Shin, Yu-Kyong, Carlson, Olga D., Fiori, Jennifer L., Xin, Li, Napora, Joshua K., Short, Ryan, Odetunde, Juliana O., Lao, Qizong, Egan, Josephine M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026810/
https://www.ncbi.nlm.nih.gov/pubmed/21283589
http://dx.doi.org/10.1371/journal.pone.0016096