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Insulin and Glucagon Regulate Pancreatic α-Cell Proliferation
Type 2 diabetes mellitus (T2DM) results from insulin resistance and β-cell dysfunction, in the setting of hyperglucagonemia. Glucagon is a 29 amino acid peptide hormone, which is secreted from pancreatic α cells: excessively high circulating levels of glucagon lead to excessive hepatic glucose outpu...
Autores principales: | Liu, Zhuo, Kim, Wook, Chen, Zhike, Shin, Yu-Kyong, Carlson, Olga D., Fiori, Jennifer L., Xin, Li, Napora, Joshua K., Short, Ryan, Odetunde, Juliana O., Lao, Qizong, Egan, Josephine M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026810/ https://www.ncbi.nlm.nih.gov/pubmed/21283589 http://dx.doi.org/10.1371/journal.pone.0016096 |
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