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β-Arrestin1 Mediates the Endocytosis and Functions of Macrophage Migration Inhibitory Factor
Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine, regulating inflammatory and immune responses. MIF binds to cell surface receptor CD74, resulting in both rapid and sustained ERK activation. It was reported that MIF-induced rapid ERK activation requires its co-receptor CD44. Bu...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026819/ https://www.ncbi.nlm.nih.gov/pubmed/21283538 http://dx.doi.org/10.1371/journal.pone.0016428 |