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β-Arrestin1 Mediates the Endocytosis and Functions of Macrophage Migration Inhibitory Factor

Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine, regulating inflammatory and immune responses. MIF binds to cell surface receptor CD74, resulting in both rapid and sustained ERK activation. It was reported that MIF-induced rapid ERK activation requires its co-receptor CD44. Bu...

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Detalles Bibliográficos
Autores principales: Xie, Lishi, Qiao, Xiaohang, Wu, Yanfang, Tang, Jie
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026819/
https://www.ncbi.nlm.nih.gov/pubmed/21283538
http://dx.doi.org/10.1371/journal.pone.0016428