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Reactive oxygen species mediate inflammatory cytokine release and EGFR-dependent mucin secretion in airway epithelial cells exposed to Pseudomonas pyocyanin

Despite the long-appreciated in vivo role of the redox-active virulence factor pyocyanin in Pseudomonas airway infections and the importance of airway epithelial cells in combating bacterial pathogens, little is known about pyocyanin’s effect on airway epithelial cells. We find that exposure of bron...

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Detalles Bibliográficos
Autores principales: Rada, Balázs, Gardina, Paul, Myers, Timothy G., Leto, Thomas L.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026888/
https://www.ncbi.nlm.nih.gov/pubmed/20962773
http://dx.doi.org/10.1038/mi.2010.62