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Codelivery of IL-7 Augments Multigenic HCV DNA Vaccine-induced Antibody as well as Broad T Cell Responses in Cynomolgus Monkeys

BACKGROUND: A crucial limitation of DNA vaccines is its weak immunogenicity, especially in terms of eliciting antibody responses in non-human primates or humans; therefore, it is essential to enhance immune responses to vaccination for the development of successful DNA vaccines for humans. METHODS:...

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Detalles Bibliográficos
Autores principales: Park, Su-Hyung, Song, Mi-Young, Nam, Hyo Jung, Im, Se Jin, Sung, Young-Chul
Formato: Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026939/
https://www.ncbi.nlm.nih.gov/pubmed/21286380
http://dx.doi.org/10.4110/in.2010.10.6.198