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NDRG2-mediated Modulation of SOCS3 and STAT3 Activity Inhibits IL-10 Production

BACKGROUND: N-myc downstream regulated gene 2 (NDRG2) is a member of the NDRG gene family. Our previous report indicated a possible role for NDRG2 in regulating the cytokine, interleukin-10 (IL-10), which is an important immunosuppressive cytokine. Several pathways, including p38-MAPK, NF-κB, and JA...

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Detalles Bibliográficos
Autores principales: Lee, Eun Byul, Kim, Aeyung, Kang, Kyeongah, Kim, Hyeree, Lim, Jong-Seok
Formato: Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026942/
https://www.ncbi.nlm.nih.gov/pubmed/21286383
http://dx.doi.org/10.4110/in.2010.10.6.219