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Interferonβ-1b Induces the Expression of RGS1 a Negative Regulator of G-Protein Signaling

We present evidence of a link between interferonβ-1b (IFN-β) and G-protein signaling by demonstrating that IFN-β can induce the expression of the negative regulator of G-protein signaling 1 (RGS1). RGS1 reduces G-protein activation and immune cell migration by interacting with heterotrimeric G-prote...

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Detalles Bibliográficos
Autores principales: Tran, Tiffany, Paz, Pedro, Velichko, Sharlene, Cifrese, Jill, Belur, Praveen, Yamaguchi, Ken D., Ku, Karin, Mirshahpanah, Parham, Reder, Anthony T., Croze, Ed
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026965/
https://www.ncbi.nlm.nih.gov/pubmed/21274427
http://dx.doi.org/10.1155/2010/529376