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Enhanced glutamate, IP3 and cAMP activity in the cerebral cortex of Unilateral 6-hydroxydopamine induced Parkinson's rats: Effect of 5-HT, GABA and bone marrow cell supplementation

Parkinson's disease is characterized by progressive cell death in the substantia nigra pars compacta, which leads to dopamine depletion in the striatum and indirectly to cortical dysfunction. Increased glutamatergic transmission in the basal ganglia is implicated in the pathophysiology of Parki...

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Detalles Bibliográficos
Autores principales: Nandhu, MS, Paul, Jes, Kuruvilla, Korah P, Malat, Anitha, Romeo, Chinthu, Paulose, CS
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3027092/
https://www.ncbi.nlm.nih.gov/pubmed/21235809
http://dx.doi.org/10.1186/1423-0127-18-5