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Evaluation of the anti-angiogenic properties of the new selective α(V)β(3 )integrin antagonist RGDechiHCit
BACKGROUND: Integrins are heterodimeric receptors that play a critical role in cell-cell and cell-matrix adhesion processes. Among them, α(V)β(3 )integrin, that recognizes the aminoacidic RGD triad, is reported to be involved in angiogenesis, tissue repair and tumor growth. We have recently synthesi...
Autores principales: | , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3027097/ https://www.ncbi.nlm.nih.gov/pubmed/21232121 http://dx.doi.org/10.1186/1479-5876-9-7 |