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Robust joint analysis allowing for model uncertainty in two-stage genetic association studies

BACKGROUND: The cost efficient two-stage design is often used in genome-wide association studies (GWASs) in searching for genetic loci underlying the susceptibility for complex diseases. Replication-based analysis, which considers data from each stage separately, often suffers from loss of efficienc...

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Detalles Bibliográficos
Autores principales: Pan, Dongdong, Li, Qizhai, Jiang, Ningning, Liu, Aiyi, Yu, Kai
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3027114/
https://www.ncbi.nlm.nih.gov/pubmed/21211060
http://dx.doi.org/10.1186/1471-2105-12-9