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Robust joint analysis allowing for model uncertainty in two-stage genetic association studies
BACKGROUND: The cost efficient two-stage design is often used in genome-wide association studies (GWASs) in searching for genetic loci underlying the susceptibility for complex diseases. Replication-based analysis, which considers data from each stage separately, often suffers from loss of efficienc...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3027114/ https://www.ncbi.nlm.nih.gov/pubmed/21211060 http://dx.doi.org/10.1186/1471-2105-12-9 |