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Comprehensive profiling of zebrafish hepatic proximal promoter CpG island methylation and its modification during chemical carcinogenesis

BACKGROUND: DNA methylation is an epigenetic mechanism associated with regulation of gene expression and it is modulated during chemical carcinogenesis. The zebrafish is increasingly employed as a human disease model; however there is a lack of information on DNA methylation in zebrafish and during...

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Detalles Bibliográficos
Autores principales: Mirbahai, Leda, Williams, Timothy D, Zhan, Huiqing, Gong, Zhiyuan, Chipman, J Kevin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3027158/
https://www.ncbi.nlm.nih.gov/pubmed/21205313
http://dx.doi.org/10.1186/1471-2164-12-3