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Signal transducer and activator of transcription 3 activation up-regulates interleukin-6 autocrine production: a biochemical and genetic study of established cancer cell lines and clinical isolated human cancer cells

BACKGROUND: Spontaneous interleukin-6 (IL-6) production has been observed in various tumors and implicated in the pathogenesis, progression and drug resistance in cancer. However, the regulation of IL-6 autocrine production in cancer cells is not fully understood. IL-6 is auto-regulated in many type...

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Detalles Bibliográficos
Autores principales: Huang, Wei-Lun, Yeh, Hsuan-Heng, Lin, Chien-Chung, Lai, Wu-Wei, Chang, Jang-Yang, Chang, Wen-Tsan, Su, Wu-Chou
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3027602/
https://www.ncbi.nlm.nih.gov/pubmed/21122157
http://dx.doi.org/10.1186/1476-4598-9-309