Heterologous Epitope-Scaffold Prime∶Boosting Immuno-Focuses B Cell Responses to the HIV-1 gp41 2F5 Neutralization Determinant

The HIV-1 envelope glycoproteins (Env) gp120 and gp41 mediate entry and are the targets for neutralizing antibodies. Within gp41, a continuous epitope defined by the broadly neutralizing antibody 2F5, is one of the few conserved sites accessible to antibodies on the functional HIV Env spike. Recentl...

Descripción completa

Detalles Bibliográficos
Autores principales: Guenaga, Javier, Dosenovic, Pia, Ofek, Gilad, Baker, David, Schief, William R., Kwong, Peter D., Karlsson Hedestam, Gunilla B., Wyatt, Richard T.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3027617/
https://www.ncbi.nlm.nih.gov/pubmed/21297864
http://dx.doi.org/10.1371/journal.pone.0016074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3027617/
https://www.ncbi.nlm.nih.gov/pubmed/21297864
http://dx.doi.org/10.1371/journal.pone.0016074

Ejemplares similares