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Dose-Dependent Thresholds of 10-ns Electric Pulse Induced Plasma Membrane Disruption and Cytotoxicity in Multiple Cell Lines

In this study, we determined the LD(50) (50% lethal dose) for cell death, and the ED(50) (50% of cell population staining positive) for propidium (Pr) iodide uptake, and phosphatidylserine (PS) externalization for several commonly studied cell lines (HeLa, Jurkat, U937, CHO-K1, and GH3) exposed to 1...

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Detalles Bibliográficos
Autores principales: Ibey, Bennett L., Roth, Caleb C., Pakhomov, Andrei G., Bernhard, Joshua A., Wilmink, Gerald J., Pakhomova, Olga N.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3027629/
https://www.ncbi.nlm.nih.gov/pubmed/21390200
http://dx.doi.org/10.1371/journal.pone.0015642