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Variance Component Analysis of a Multi-Site Study for the Reproducibility of Multiple Reaction Monitoring Measurements of Peptides in Human Plasma

BACKGROUND: In the Addona et al. paper (Nature Biotechnology 2009), a large-scale multi-site study was performed to quantify Multiple Reaction Monitoring (MRM) measurements of proteins spiked in human plasma. The unlabeled signature peptides derived from the seven target proteins were measured at ni...

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Detalles Bibliográficos
Autores principales: Xia, Jessie Q., Sedransk, Nell, Feng, Xingdong
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3027641/
https://www.ncbi.nlm.nih.gov/pubmed/21298095
http://dx.doi.org/10.1371/journal.pone.0014590