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A Modified Vaccinia Ankara Virus (MVA) Vaccine Expressing African Horse Sickness Virus (AHSV) VP2 Protects Against AHSV Challenge in an IFNAR −/− Mouse Model

African horse sickness (AHS) is a lethal viral disease of equids, which is transmitted by Culicoides midges that become infected after biting a viraemic host. The use of live attenuated vaccines has been vital for the control of this disease in endemic regions. However, there are safety concerns ove...

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Detalles Bibliográficos
Autores principales: Castillo-Olivares, Javier, Calvo-Pinilla, Eva, Casanova, Isabel, Bachanek-Bankowska, Katarzyna, Chiam, Rachael, Maan, Sushila, Nieto, Jose Maria, Ortego, Javier, Mertens, Peter Paul Clement
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3027694/
https://www.ncbi.nlm.nih.gov/pubmed/21298069
http://dx.doi.org/10.1371/journal.pone.0016503