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Glucagon Receptor Knockout Prevents Insulin-Deficient Type 1 Diabetes in Mice

OBJECTIVE: To determine the role of glucagon action in the metabolic phenotype of untreated insulin deficiency. RESEARCH DESIGN AND METHODS: We compared pertinent clinical and metabolic parameters in glucagon receptor-null (Gcgr(−/−)) mice and wild-type (Gcgr(+/+)) controls after equivalent destruct...

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Detalles Bibliográficos
Autores principales:	Lee, Young, Wang, May-Yun, Du, Xiu Quan, Charron, Maureen J., Unger, Roger H.
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2011
Materias:	Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3028337/ https://www.ncbi.nlm.nih.gov/pubmed/21270251 http://dx.doi.org/10.2337/db10-0426

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