Selective Inactivation of c-Jun NH(2)-Terminal Kinase in Adipose Tissue Protects Against Diet-Induced Obesity and Improves Insulin Sensitivity in Both Liver and Skeletal Muscle in Mice

OBJECTIVE: Obesity is associated with increased activation of the c-Jun NH(2)-terminal kinase (JNK) in several metabolic organs, including adipose tissue, liver, and skeletal muscle. In this study, we aimed to define the role of JNK activation in adipose tissue in the development of obesity-related...

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Detalles Bibliográficos
Autores principales: Zhang, Xinmei, Xu, Aimin, Chung, Sookja K., Cresser, Justin H.B., Sweeney, Gary, Wong, Rachel L.C., Lin, Anning, Lam, Karen S.L.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Obesity Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3028348/
https://www.ncbi.nlm.nih.gov/pubmed/21270260
http://dx.doi.org/10.2337/db10-0650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3028348/
https://www.ncbi.nlm.nih.gov/pubmed/21270260
http://dx.doi.org/10.2337/db10-0650

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