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Selective Inactivation of c-Jun NH(2)-Terminal Kinase in Adipose Tissue Protects Against Diet-Induced Obesity and Improves Insulin Sensitivity in Both Liver and Skeletal Muscle in Mice
OBJECTIVE: Obesity is associated with increased activation of the c-Jun NH(2)-terminal kinase (JNK) in several metabolic organs, including adipose tissue, liver, and skeletal muscle. In this study, we aimed to define the role of JNK activation in adipose tissue in the development of obesity-related...
Autores principales: | Zhang, Xinmei, Xu, Aimin, Chung, Sookja K., Cresser, Justin H.B., Sweeney, Gary, Wong, Rachel L.C., Lin, Anning, Lam, Karen S.L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3028348/ https://www.ncbi.nlm.nih.gov/pubmed/21270260 http://dx.doi.org/10.2337/db10-0650 |
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