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The Protective Role of Smad7 in Diabetic Kidney Disease: Mechanism and Therapeutic Potential

OBJECTIVE: Although Smad3 has been considered as a downstream mediator of transforming growth factor-β (TGF-β) signaling in diabetes complications, the role of Smad7 in diabetes remains largely unclear. The current study tests the hypothesis that Smad7 may play a protective role and has therapeutic...

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Detalles Bibliográficos
Autores principales: Chen, Hai Yong, Huang, Xiao R., Wang, Wansheng, Li, Jin Hua, Heuchel, Rainer L., Chung, Arthur C.K., Lan, Hui Yao
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3028360/
https://www.ncbi.nlm.nih.gov/pubmed/20980457
http://dx.doi.org/10.2337/db10-0403