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The Protective Role of Smad7 in Diabetic Kidney Disease: Mechanism and Therapeutic Potential
OBJECTIVE: Although Smad3 has been considered as a downstream mediator of transforming growth factor-β (TGF-β) signaling in diabetes complications, the role of Smad7 in diabetes remains largely unclear. The current study tests the hypothesis that Smad7 may play a protective role and has therapeutic...
Autores principales: | Chen, Hai Yong, Huang, Xiao R., Wang, Wansheng, Li, Jin Hua, Heuchel, Rainer L., Chung, Arthur C.K., Lan, Hui Yao |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3028360/ https://www.ncbi.nlm.nih.gov/pubmed/20980457 http://dx.doi.org/10.2337/db10-0403 |
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