Resveratrol Improves Oxidative Stress and Protects Against Diabetic Nephropathy Through Normalization of Mn-SOD Dysfunction in AMPK/SIRT1-Independent Pathway

OBJECTIVE: Despite the beneficial effects of resveratrol (RSV) on cardiovascular disease and life span, its effects on type 2 diabetic nephropathy remain unknown. This study examined the renoprotective effects of RSV in db/db mice, a model of type 2 diabetes. RESEARCH DESIGN AND METHODS: db/db mice...

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Detalles Bibliográficos
Autores principales: Kitada, Munehiro, Kume, Shinji, Imaizumi, Noriko, Koya, Daisuke
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3028365/
https://www.ncbi.nlm.nih.gov/pubmed/21270273
http://dx.doi.org/10.2337/db10-0386