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A CD36-dependent pathway enhances macrophage and adipose tissue inflammation and impairs insulin signalling

AIMS: Obesity and hyperlipidaemia are associated with insulin resistance (IR); however, the mechanisms responsible remain incompletely understood. Pro-atherogenic hyperlipidaemic states are characterized by inflammation, oxidant stress, and pathophysiologic oxidized lipids, including ligands for the...

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Detalles Bibliográficos
Autores principales: Kennedy, David J., Kuchibhotla, Sai, Westfall, Kristen M., Silverstein, Roy L., Morton, Richard E., Febbraio, Maria
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3028977/
https://www.ncbi.nlm.nih.gov/pubmed/21088116
http://dx.doi.org/10.1093/cvr/cvq360