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A CD36-dependent pathway enhances macrophage and adipose tissue inflammation and impairs insulin signalling
AIMS: Obesity and hyperlipidaemia are associated with insulin resistance (IR); however, the mechanisms responsible remain incompletely understood. Pro-atherogenic hyperlipidaemic states are characterized by inflammation, oxidant stress, and pathophysiologic oxidized lipids, including ligands for the...
Autores principales: | Kennedy, David J., Kuchibhotla, Sai, Westfall, Kristen M., Silverstein, Roy L., Morton, Richard E., Febbraio, Maria |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3028977/ https://www.ncbi.nlm.nih.gov/pubmed/21088116 http://dx.doi.org/10.1093/cvr/cvq360 |
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