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Glucose Depletion in the Airway Surface Liquid Is Essential for Sterility of the Airways

Diabetes mellitus predisposes the host to bacterial infections. Moreover, hyperglycemia has been shown to be an independent risk factor for respiratory infections. The luminal surface of airway epithelia is covered by a thin layer of airway surface liquid (ASL) and is normally sterile despite consta...

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Detalles Bibliográficos
Autores principales: Pezzulo, Alejandro A., Gutiérrez, Jeydith, Duschner, Kelly S., McConnell, Kelly S., Taft, Peter J., Ernst, Sarah E., Yahr, Timothy L., Rahmouni, Kamal, Klesney-Tait, Julia, Stoltz, David A., Zabner, Joseph
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029092/
https://www.ncbi.nlm.nih.gov/pubmed/21311590
http://dx.doi.org/10.1371/journal.pone.0016166