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Glucose Depletion in the Airway Surface Liquid Is Essential for Sterility of the Airways
Diabetes mellitus predisposes the host to bacterial infections. Moreover, hyperglycemia has been shown to be an independent risk factor for respiratory infections. The luminal surface of airway epithelia is covered by a thin layer of airway surface liquid (ASL) and is normally sterile despite consta...
Autores principales: | Pezzulo, Alejandro A., Gutiérrez, Jeydith, Duschner, Kelly S., McConnell, Kelly S., Taft, Peter J., Ernst, Sarah E., Yahr, Timothy L., Rahmouni, Kamal, Klesney-Tait, Julia, Stoltz, David A., Zabner, Joseph |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029092/ https://www.ncbi.nlm.nih.gov/pubmed/21311590 http://dx.doi.org/10.1371/journal.pone.0016166 |
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