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Impact of Sarcoplasmic Reticulum Calcium Release on Calcium Dynamics and Action Potential Morphology in Human Atrial Myocytes: A Computational Study

Electrophysiological studies of the human heart face the fundamental challenge that experimental data can be acquired only from patients with underlying heart disease. Regarding human atria, there exist sizable gaps in the understanding of the functional role of cellular Ca(2+) dynamics, which diffe...

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Detalles Bibliográficos
Autores principales: Koivumäki, Jussi T., Korhonen, Topi, Tavi, Pasi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029229/
https://www.ncbi.nlm.nih.gov/pubmed/21298076
http://dx.doi.org/10.1371/journal.pcbi.1001067