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Detecting Remote Evolutionary Relationships among Proteins by Large-Scale Semantic Embedding

Virtually every molecular biologist has searched a protein or DNA sequence database to find sequences that are evolutionarily related to a given query. Pairwise sequence comparison methods—i.e., measures of similarity between query and target sequences—provide the engine for sequence database search...

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Detalles Bibliográficos
Autores principales: Melvin, Iain, Weston, Jason, Noble, William Stafford, Leslie, Christina
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029239/
https://www.ncbi.nlm.nih.gov/pubmed/21298082
http://dx.doi.org/10.1371/journal.pcbi.1001047