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A Meta-Analysis of Genome-Wide Association Scans Identifies IL18RAP, PTPN2, TAGAP, and PUS10 As Shared Risk Loci for Crohn's Disease and Celiac Disease

Crohn's disease (CD) and celiac disease (CelD) are chronic intestinal inflammatory diseases, involving genetic and environmental factors in their pathogenesis. The two diseases can co-occur within families, and studies suggest that CelD patients have a higher risk to develop CD than the general...

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Detalles Bibliográficos
Autores principales: Festen, Eleonora A. M., Goyette, Philippe, Green, Todd, Boucher, Gabrielle, Beauchamp, Claudine, Trynka, Gosia, Dubois, Patrick C., Lagacé, Caroline, Stokkers, Pieter C. F., Hommes, Daan W., Barisani, Donatella, Palmieri, Orazio, Annese, Vito, van Heel, David A., Weersma, Rinse K., Daly, Mark J., Wijmenga, Cisca, Rioux, John D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029251/
https://www.ncbi.nlm.nih.gov/pubmed/21298027
http://dx.doi.org/10.1371/journal.pgen.1001283