The Substrate-Driven Transition to an Inward-Facing Conformation in the Functional Mechanism of the Dopamine Transporter

BACKGROUND: The dopamine transporter (DAT), a member of the neurotransmitter:Na(+) symporter (NSS) family, terminates dopaminergic neurotransmission and is a major molecular target for psychostimulants such as cocaine and amphetamine, and for the treatment of attention deficit disorder and depressio...

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Detalles Bibliográficos
Autores principales: Shan, Jufang, Javitch, Jonathan A., Shi, Lei, Weinstein, Harel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029329/
https://www.ncbi.nlm.nih.gov/pubmed/21298009
http://dx.doi.org/10.1371/journal.pone.0016350

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029329/
https://www.ncbi.nlm.nih.gov/pubmed/21298009
http://dx.doi.org/10.1371/journal.pone.0016350

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