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HNF4alpha Dysfunction as a Molecular Rational for Cyclosporine Induced Hypertension
Induction of tolerance against grafted organs is achieved by the immunosuppressive agent cyclosporine, a prominent member of the calcineurin inhibitors. Unfortunately, its lifetime use is associated with hypertension and nephrotoxicity. Several mechanism for cyclosporine induced hypertension have be...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029342/ https://www.ncbi.nlm.nih.gov/pubmed/21298017 http://dx.doi.org/10.1371/journal.pone.0016319 |