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Double-Positive CD21+CD27+ B Cells Are Highly Proliferating Memory Cells and Their Distribution Differs in Mucosal and Peripheral Tissues

BACKGROUND: Several B-cell defects arise in HIV infected patients, particularly in patients with chronic infection and high viral load. Loss of memory B cells (CD27(+) B cells) in peripheral blood and lymphoid tissues is one of the major B cell dysfunctions in HIV and simian immunodeficiency virus (...

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Detalles Bibliográficos
Autores principales: Das, Arpita, Xu, Huanbin, Wang, Xiaolei, Yau, Canddy L., Veazey, Ronald S., Pahar, Bapi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029363/
https://www.ncbi.nlm.nih.gov/pubmed/21304587
http://dx.doi.org/10.1371/journal.pone.0016524