Loss of Pten Causes Tumor Initiation Following Differentiation of Murine Pluripotent Stem Cells Due to Failed Repression of Nanog

Pluripotent stem cells (PSCs) hold significant promise in regenerative medicine due to their unlimited capacity for self-renewal and potential to differentiate into every cell type in the body. One major barrier to the use of PSCs is their potential risk for tumor initiation following differentiatio...

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Detalles Bibliográficos
Autores principales: Lindgren, Anne G., Natsuhara, Kyle, Tian, E., Vincent, John J., Li, Xinmin, Jiao, Jing, Wu, Hong, Banerjee, Utpal, Clark, Amander T.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029365/
https://www.ncbi.nlm.nih.gov/pubmed/21304588
http://dx.doi.org/10.1371/journal.pone.0016478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3029365/
https://www.ncbi.nlm.nih.gov/pubmed/21304588
http://dx.doi.org/10.1371/journal.pone.0016478

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